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http://paper.sci.ui.ac.id/jspui/handle/2808.28/144
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DC Field | Value | Language |
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dc.contributor.author | Nurjayadi, Muktiningsih | - |
dc.contributor.author | Apriyani, Dea | - |
dc.contributor.author | Hasan, Umar | - |
dc.contributor.author | Santoso, Imam | - |
dc.contributor.author | Kurniadewi, Fera | - |
dc.contributor.author | Kartika, Irma Ratna | - |
dc.contributor.author | Agustini, Kurnia | - |
dc.contributor.author | Puspasari, Fernita | - |
dc.contributor.author | Natalia, Dessy | - |
dc.contributor.author | Mangunwardoyo, Wibowo | - |
dc.date.accessioned | 2016-08-21T06:28:06Z | - |
dc.date.available | 2016-08-21T06:28:06Z | - |
dc.date.issued | 2015-05 | - |
dc.identifier.issn | 18766196 | - |
dc.identifier.other | 10.1016/j.proch.2016.01.037e | en_US |
dc.identifier.uri | http://paper.sci.ui.ac.id/jspui/handle/2808.28/144 | - |
dc.description.abstract | Salmonella typhimurium, that cause typhoid fever in mice was used as a model to study typhoid fever in humans. This study is aimed to determine the immunogenicity of recombinant protein of Fim-C-S. typhimurium and specificity of antibody anti-recombinant protein of Fim-C-S. typhimurium in ddY mice. The immunogenicity studies by ELISA indicated that recombinant protein of Fim-C-S. typhimurium evokes strong immune response in ddY mice, particularly in experiment group. The specificity evaluated by Western Immunobloting technique indicated that the antibody anti-recombinant protein of Fim-C-S. typhimurium can detect the 31 kDa of recombinant protein of Fim-C-S. typhimurium as an antigen. This data reported that recombinant protein of Fim-C-S. typhimurium is immunogenic and the antibody anti-recombinant protein of Fim-C-S. typhimurium is specific. The results of this study can be used as a model to develop recombinant vaccine candidate against typhoid. | en_US |
dc.language.iso | en_US | en_US |
dc.relation.ispartofseries | Volume 18; | - |
dc.source | Procedia Chemistry Volume 18, Pages 237-245 (2016) | en_US |
dc.source.uri | http://www.sciencedirect.com/science/article/pii/S1876619616000383 | en_US |
dc.subject | Salmonella typhimurium | en_US |
dc.subject | typhoid fever | en_US |
dc.subject | recombinant protein Fim-C-Salmonella typhimurium antibody | en_US |
dc.subject | recombinant vaccine | en_US |
dc.title | Immunogenicity and Specificity of Anti recombinant Protein FimC-Salmonella typhimurium Antibody as a Model to Develop Typhoid Vaccine | en_US |
dc.type | Article | en_US |
Appears in Collections: | Journal Collection |
Files in This Item:
File | Description | Size | Format | |
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Wibowo.ProcediaChemistry.2016.pdf | 530,99 kB | Adobe PDF | View/Open Request a copy |
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